Substantial investments have been made into constructing pest-proof netting fences (‘cluster fences’) around multiple grazing properties in western Queensland. Effective control of many vertebrate pests (e.g. wild dogs, kangaroos, feral pigs and feral goats) is now possible across large areas, by denying immigration, offering widespread and substantial benefits to agriculture and the environment. Similar fences are proposed for more arid areas in southern rangelands of WA, but the optimal cluster size and likely benefits for particular land types and production systems are unknown. This project brings together and expands the scope of existing studies to inform future cluster fencing activities.